Unlock savings on chemical innovation, formula development and process enhancement. Chemical manufacturers, formulators, intermediates producers, polymer specialists, coatings and specialty‑chemical firms in the U.S. invest heavily in new compounds, reactions, process scale‑up and sustainability innovations — and many of these expenditures qualify for the federal R&D Tax Credit under IRC §41 plus state‑based incentives.

Examples of qualifying activities in chemicals production
- Formula & Polymer Innovation Developing a new coating polymer with improved adhesion and lower VOC emissions, experimenting with catalysts for alternative feedstocks, medium‑scale trials of novel intermediates.
- Process & Reaction Scale‑Up Translating a bench‑scale reaction to pilot/plant scale, adjusting reaction parameters (temperature/pressure/time) to optimise yield, reducing cycle time, minimizing by‑product formation, validating through instrumentation and analytics.
- Manufacturing Line/Equipment Innovation Installing or adapting specialised reactors, sensor systems, process‑control automation, waste‑heat recovery, inline analytics, advanced mixing or separation methods, pilot trial runs for new feedstock or reaction technology.
- Sustainability & Environmental Enhancement Replacing fossil feedstocks with bio‑based alternatives, designing processes requiring less water/energy, trialling novel waste‑reduction or recycling loops, validating new process controls or sensors for emissions monitoring.
What qualifies as R&D in the chemical manufacturing sector?

To qualify, your chemical‑industry activities must:
- Aim at a permitted purpose — such as a new or improved chemical formula, intermediate, polymer/excipient, new catalyst, a process improvement (yield, cycle time, energy‑use), or sustainability enhancement (lower waste, greener feedstocks).
- Tackle technical uncertainty — for example: “Can this new polymer blend achieve target mechanical properties and processing tolerances while reducing toxic‑by‑products?”, “Will a scaled‑up reaction from lab‑bench deliver the same yield and safety profile in production environment?”, “Can a new catalyst reduce reaction time by 30% while maintaining product quality and regulatory compliance?”
- Use a process of experimentation — including lab‑scale formulation testing, pilot‑batches, process modelling, alternative route trials, failure analysis, scale‑up validation, process‑design iterations.
- Be technological in nature — grounded in chemical engineering, materials science, process engineering, analytical chemistry, instrumentation/automation, or software modelling of chemical processes.
Qualified Research Expenses (QREs)
In the chemical sector, relevant expense categories include:
Roles commonly involved in qualifying activities
- Chemical/process engineers developing new reactions or process scale‑up
- Analytical chemists or research scientists validating new compounds or catalysts
- Automation/control engineers installing process‑monitoring systems or inline analytics
- Pilot‑plant engineers managing small‑scale trials and transition to production
- Sustainability engineers leading replacements of feedstocks or waste‑reduction loops
- External research labs or specialized materials/catalyst testers validating new chemistries
What does not qualify
- Routine production of known compounds or intermediates without experimentation or technical uncertainty
- Standard scale‑up of production using established methods without modifications/trials
- General business functions: sales, marketing, administrative tasks, order fulfilment
- Land acquisition, building expansions, or standard machine purchases not tied to an active research/test program
Compliance and Documentation
Following the One Big Beautiful Bill Act (OBBBA) signed July 4, 2025, §174 now allows immediate expensing of domestic research expenses for tax years beginning on or after January 1, 2025. Taxpayers may also elect optional amortization under new §174A. Foreign research expenses must still be amortized over 15 years. This is separate from the §41 credit but impacts overall tax planning.
Recommended documentation for chemical‑industry R&D:
- Project briefs/hypotheses (e.g., “Will a new catalyst reduce reaction time by 25% while maintaining >99% purity and reducing by‑products by 15%?”, “Scale‑up of polymer reaction from 10 kg to 1000 kg while maintaining mechanical properties within spec”)
- Lab/trial logs: reaction conditions, yield/time data, failed experiments and alternatives, pilot‑plant test sheets, analytics and instrumentation outputs
- Time‑tracking for engineers/scientists/support staff engaged in the experimentation
- Invoices for feedstocks, materials, sensors/analytics equipment, contract lab services; pilot‑batch data; scale‑up test results
- Version history: iterations of chemistry, process parameters, equipment changes, sample test results, process data and conclusions/next‑steps Maintaining robust documentation helps satisfy the §41 four‑part test (permitted purpose, technical uncertainty, process of experimentation, technological in nature).
Frequently Asked Questions
Yes — if your company is developing new or improved formulas, catalysts, polymer blends, scaling up novel processes, implementing process‑control/automation systems, or investigating sustainability innovations rather than executing routine production.
Wages for scientists/engineers, supplies consumed in experimentation (chemicals, catalysts, pilot‑batch feedstocks), software tools for modelling/analytics, and third‑party contract research services connected to R&D programmes.
Developing a new coating polymer, scaling a lab‑reaction to pilot/plant scale, integrating sensors for process monitoring, trialling bio‑based feedstocks, performing process‑control automation for yield optimisation, reducing energy or water footprint in reaction systems.
Routine manufacturing runs of known chemicals without experimentation, standard scale‑up following proven process without modification/tests, general business/support tasks, equipment purchases solely for production scaling without a research/test component.
Credit value depends on size of innovation, years of eligible spending and documentation quality. Many chemical‑industry firms that properly document their R&D enjoy credit values in the range of ~20‑22% of qualified research expenses (federal + state combined) when optimised.
Keep project briefs/hypotheses (e.g., “Will new catalyst achieve same conversion in 30% less time at scale while reducing by‑product formation by 10%?”), track trial logs, record failed alternatives, employee/time‑tracking records, invoices for materials/analytics/third‑party services, pilot‑scale data, process‑iteration summaries, and next‑step conclusions.
Next Steps
Use our calculator to estimate your potential federal and state benefits
Schedule a consultation to structure your row crop research activities
If you are innovating in agriculture, you may already be doing R&D. Let's make sure you are rewarded for it.
Contact Strike Tax Advisory
Ready to maximize your R&D tax credits? Get in touch with our team of experts.


